@article {p430,
	abstract = {
Objectives Galectin-3, a member of galectines, a family of β-galactoside-specific lectins, has been reported to propagate vascular inflammation. The role of galectin-3 in carotid atherosclerosis is controversial. The aim of this study was to investigate the relationship of galectin-3 with plaque vulnerability in patients with high grade carotid stenosis. Methods This was a cross sectional study of patients undergoing carotid endarterectomy (CEA). Carotid plaques obtained from 78 consecutive patients (40 symptomatic [SG], 38 asymptomatic [AG]) undergoing {CEA} were histologically analyzed for galectin-3, macrophages (CD68) and laminin. Pre-operatively the biochemical profile and plaque echogenicity (gray-scale median, GSM) score were determined. Results There were no significant differences in clinical and demographic parameters between {SG} and {AG} (p> .05). The {SG} had a lower {GSM} score  and a smaller positive stained area for galectin-3.},
	author = {N.P.E. Kadoglou and G.S. Sfyroeras and A. Spathis and C. Gkekas and A. Gastounioti and G. Mantas and K.S. Nikita and P. Karakitsos and C.D. Liapis},
	citation-key = {p430},
	doi = {http://dx.doi.org/10.1016/j.ejvs.2014.10.009},
	issn = {1078-5884},
	journal = {European Journal of Vascular and Endovascular Surgery},
	keywords = {Plaque vulnerability},
	pages = {-},
	title = {Galectin-3, Carotid Plaque Vulnerability, and Potential Effects of Statin Therapy},
	type = {article},
	url = {http://www.sciencedirect.com/science/article/pii/S1078588414005772},
	year = {2014}
}