Development of advanced computational algorithms and tools to assist the design of functional interventions in Parkinson's disease and resistant epilepsy

Partners: National Technical University of Athens (School of Electrical and Computer Engineering), National & Kapodistrian University of Athens (Medical School), Bio-Signal Analysis Laboratory-Electrical and Computer Engineering Department (University of Houston), MEDTRON SYSTEMS INC. CORPORATION

Duration: 2006 - 2009

The surgical treatment of chronic neurological diseases that cannot be adequately treated by medicines is widely applied for two diseases: epilepsy and Parkinson's disease. This project aims at the development of advanced computational algorithms and software tools for the digital processing of brain signals (EEG, microelectrode recordings) and for the computational modelling of brain structures/functions based on individualized anatomical and neurophysiological data. The computational tools that will be developed will mainly aim at the establishment of quantitative features (measures) to assist diagnosis, treatment and evaluation of therapeutic outcome in Parkinson's disease and epilepsy. Furthermore, the applicability of the developed algorithms and computational tools to other neurological/ neuropsychiatric diseases will be investigated.